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Semaglutide is a prescription medication used to treat obesity and help with weight loss. It is a glucagon-like peptide-1 (GLP-1) receptor agonist, which works by increasing feelings of fullness and reducing hunger. This medication is prescribed to individuals with a body mass index (BMI) of 30 or higher, or individuals with a BMI of 27 or higher with comorbidities such as high blood pressure, type 2 diabetes, or high cholesterol.
Semaglutide is taken once a week, either as a subcutaneous injection or as a once-weekly tablet. It is important to note that this medication should be used in conjunction with a reduced-calorie diet and increased physical activity. The recommended dose of semaglutide is 0.5 mg or 1.0 mg once weekly. The dose may be adjusted to a maximum of 2.4 mg once weekly if needed.
The safety and efficacy of semaglutide have been demonstrated in multiple clinical trials. In a clinical trial of 3,731 adults with obesity, participants taking semaglutide lost an average of 8.7% of their body weight, compared to 2.2% for those taking a placebo. In another clinical trial of 2,487 adults with obesity, semaglutide was found to be superior to a placebo for weight loss, with an average weight loss of 9.2% compared to 2.6%.
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Semaglutide is generally well-tolerated, but like any medication, it may cause side effects. The most common side effects include nausea, diarrhea, and vomiting. These side effects typically resolve on their own within the first few weeks of treatment. In rare cases, serious side effects may occur, including pancreatitis and kidney problems. It is important to talk to your doctor if you experience any unusual symptoms or side effects while taking semaglutide.
In conclusion, semaglutide is a medication that can be effective for treating obesity and promoting weight loss. However, it is important to remember that this medication should be used in conjunction with a reduced-calorie diet and increased physical activity, and that it may cause side effects. If you have questions about semaglutide or are considering using it to help with your weight loss goals, talk to your doctor. They can help you determine if semaglutide is right for you and help you weigh the risks and benefits.
